The aim of the CardioVascular Research Grid (CVRG) project is to create a grid infrastructure for sharing cardiovascular data and data analysis tools. The CVRG will support national and international multi-institutional collaborations in cardiovascular science, and will build on and extend tools developed in the caBIG and BIRN projects. The CVRG project is supported by the National Heart Lung & Blood Institute. The project is based at the Institute for Computational Medicine at Johns Hopkins University, in collaboration with the Department of Biomedical Informatics at The Ohio State University, and the Center for Research in Biological Systems at the University of California, San Diego.